Click here if you are having problems viewing this email.

Laboratory Instrumentation News is published by the publisher of American Laboratory and American Biotechnology Laboratory.

  In this June 2008 issue

Welcome to the World of Savings in High Quality Refurbished Lab Equipment
Advertisement

Are you ready to experience the luxury of owning high quality refurbished lab equipment at a fraction of the price of new? We have one of the largest selections of used lab equipment under one roof, ranging from stirrers and vortexers to HPLC and GC/MS systems. Our friendly and knowledgeable sales staff will help you find the piece of equipment you need to complete your mission and help you create the next mission. Please call or click today!!!
American Laboratory Trading

Click here for more information

Accelerated Solvent Extraction With Acid Pretreatment for Improved Laboratory Productivity
by Brian Dorich, Eric Francis, Brett Murphy, Bruce Richter, and Sheldon Henderson
           Sample preparation, specifically solvent extraction, is an important beginning step in the analytical process. If the extraction procedure is incomplete, the results are inaccurate analyses or poor recoveries. Analysts have used an array of solvent extraction techniques ranging from Soxhlet, shaking, sonication, and blending. Accelerated solvent extraction (ASE®) technology is a flow-through solvent extraction system that helps increase productivity and sample throughput while reducing preparation cost and providing a platform for automation.

Click here to read more.

Malvern Instruments Aquires Viscotek Corp.
          Materials characterization company Malvern Instruments has acquired Viscotek Corp., a leading provider of chromatography solutions for the characterization of natural and synthetic polymers and proteins.
Free Best Practices White Paper for Managing Lab Chemical Inventory
Advertisement

BEST PRACTICES WHITE PAPER: In-depth Best Practices white paper focuses on leveraging operational excellence strategies to improve chemical safety and inventory data management.

ChemSW, Inc.’s definitive white paper details best practices in chemical inventory management, providing insights to ensure system adoption and successful incorporation into lab processes.

Reasons why systems fail and why they succeed are examined, the true costs associated with chemical inventory management, and how to address any regulatory requirement from 21-CFR-Part 11 to the new DHS 6-CFR-27 chemical security standard.

For your copy, visit http://www.chemsw.com/al806bp.htm.

Company Name: ChemSW
Phone: (707) 864-0845
Email: info@chemsw.com
Web: www.ChemSW.com

In Situ Gas Heating and Real-Time 3-D Imaging Using a Transmission Electron Microscope
by Xiao Feng Zhang
          In situ atomic resolution imaging with gas injection and sample heating, and realtime three-dimensional structural and chemical characterizations are important features of the Hitachi H-9500 300 kV transmission electron microscope (TEM) (Hitachi High Technologies America, Inc., Pleasanton, CA). In situ gas environmental transmission electron microscopy (E-TEM) has been well recognized for its irreplaceable role in performing dynamic observation. The purpose of the E-TEM is to introduce gas into the specimen chamber of a TEM to study the gas–solid interactions between sample and gas. Since TEM works at high vacuum, gas is typically introduced into the microscope in two ways. The first method is to seal a sample in an environmental cell (E-cell) confined by electron transparent windows. The advantages of this window-type E-cell include simple design and low cost, but atomic resolution is difficult to achieve, and heating the sample is risky because the window materials may be damaged at elevated temperatures, causing gas to leak into the microscope column.

Click here to read more.

Protagen AG has Entered Into an International Collaboration
          Protagen AG, a leading provider of products, services, and software solutions for protein research, has entered into an international collaboration to develop antibodies against liver proteins with the Centre for Applied Proteomics (ZAP) (Dortmund), Schunde Kangdi Antibody Biotech (Foshan, China), and the Beijing Proteome Research Centre (Beijing, China).
Independent technical report evaluates protein precipitation microplates
Advertisement

Porvair

A technical report based upon an independent in-depth evaluation of currently commercially available protein precipitation microplates is available from Porvair Sciences Ltd.

The use of protein precipitation as a method for sample preparation is widely used within the pharmaceutical research community. Consequently the need to automate the technique, to save technician time, has spurned a new generation of special multi-well filtration microplates adaptable for automated sample preparation using liquid handling equipment.

Undertaken by a drug metabolism department of a major multinational pharmaceutical company, the evaluation concluded that the p3 microplate from Porvair Sciences represents the current benchmark in protein precipitation technology.

To request your free copy of the technical report please visit www.porvair-sciences.com/p3report.htm

Porvair Sciences Ltd.
Unit 6, Shepperton Business Park
Govett Avenue
Shepperton
Middlesex TW17 8BA
UK
Tel.: +44-1932-240255
E-mail: int.sales@porvair-sciences.com
www.porvair-sciences.com

A Real-Time Interface of Liquid Chromatography and Infrared Spectroscopy
by Tom Kearney and James L. Dwyer
           The analysis of multicomponent samples usually involves two separate laboratory techniques: 1) fractionation of the sample into its discrete components, and 2) identification/quantification of components. Chromatography, in particular liquid chromatography, is the most commonly used fractionation technique. Spectrometry in its various forms is prevalent for identification.

Click here to read more.

METTLER TOLEDO Quick-Brix™ 60
Advertisement

Easy-to-use portable BRIX meter

Results in three steps - Squeeze liquid onto the prism, press the read key, get the result.

Measurement on location - Reduces errors, provides faster results. Splash-proof and comes with a handy wrist-strap.

Digital measurement - Eliminates operator dependence. Quick-Brix™ 60 yields the correct result irrespective of the operator. Measures Brix in the range from 0 - 60% with an accuracy of ± 0.2%. Built-in temperature compensation.

Also available, Quick-Brix 90 for the range 0 – 90% Brix.

http://www.mt.com/quick

Evaluating Candidate Lead Compounds by Rapid Analysis of Drug Interactions with Human Serum Albumin
by Vered Bronner, Oded Nahshol, and Tsafrir Bravman
          Human serum albumin (HSA) plays a fundamental role in the transport of drugs, metabolites, and endogenous ligands. Binding to HSA controls the free, active concentration of a drug, provides a reservoir for a long duration of action, and ultimately affects drug absorption, distribution, metabolism, and excretion (ADME), making HSA binding a key parameter in evaluating candidate lead compounds during drug design. A broad range of approaches has been used to study drug–protein binding, including equilibrium dialysis, filtration, centrifugation, and chromatography. However, the resolution, reproducibility, and throughput of these methods are limiting.

Click here to read more.

Mettler-Toledo Inc. Moves its Canadian Headquarters
          As part of an ongoing commitment to growth in the Canadian market, Mettler-Toledo Inc. moved its Canadian headquarters to a new location. A leading global supplier of precision instruments and the world´s largest manufacturer and marketer of weighing instruments, the company´s new site positions it much closer to a core customer base and to its GTA employee base. The 13,788-ft2 facility will be home to the Canadian operations of Mettler-Toledo Inc. and sister company, Rainin Instrument LLC, Canada.
EST Analytical HS9000
Advertisement
EST Analytical HS9000
The dual needle's ability to continually sweep the headspace for concentration on the optional adsorbent trap or at the analytical column give the user the flexibility to increase the sensitivity of the analysis when needed. Other novel standard features such as the ability to make both traditional time based injections and traditional fixed loop injections within the same schedule, 90 position carousel, constant heat mode, multiple headspace extractions, and bulk sampling make the Markelov HS9000 the most versatile headspace sampler available for a wide variety of applications. For more information CLICK HERE or click below to download a paper given at this years Pittsburgh Conference.

EST Analytical
503 Commercial Drive Fairfield, OH 45014
Phone: 513 642-0100
E-mail: newsletter@estanalytical.com
www.estanalytical.com
A Microfluidic Approach to Patch-Clamp-Based Ion Channel Safety Testing
by Fredrik Pettersson, Christer Johansson, Susanne Braum, and Jon Sinclair
          The development of patch-clamping, whole-cell, and single-channel recording has made in-depth studies of ion channels possible in a wide variety of preparations. An important aspect of ion channel studies is safety testing, since it has been found that certain drugs affect ion channels governing heart function. The activity of many ion channels is temperature dependent; thus it is important to study ion channels at different temperatures. Temperature is especially important in safety screening applications in which variations from physiological conditions could lead to misleading results and erroneous conclusions. To support temperature-controlled safety screening, the Dynaflow® temperature control system (Cellectricon, Gothenburg, Sweden) was developed. The system combines the Dynaflow DF-8 Pro II chip with its controlled solution exchange and low compound consumption with a stage that provides precise temperature control.

Click here to read more.
OmniStarTM Gas Analysis System
Advertisement

The Pfeiffer Vacuum OmniStarTM gas analysis system is a high performance, flexible quadrupole mass spectrometer in a compact benchtop package. OmniStar is capable of simultaneously monitoring up to 64 gases from 100% to below 10ppb with available mass ranges of 1–100, 1–200 and 1–300 amu. Dual filaments are standard with the OmniStar for maximum up-time as well as a secondary electron multiplier detector for fast, low level measurements. Pressure is constantly monitored via a Pfeiffer Vacuum Full Range gauge and the filaments and detector are interlocked based on a user defined trip level. Integral bakeout and inlet heaters are included to reduce backgrounds and prevent condensation.

For more information, CLICK HERE

AMTEK, Inc. has Aquired Newage Testing Instruments
AMETEK, Inc. has acquired Newage Testing Instruments, a privately held manufacturer of hardness testing equipment used in a broad range of industries, including aerospace, oil exploration, and defense. Newage´s differentiated measurement technology, coupled with its market-leading automation and application software, complements AMETEK´s growing product line of materials testing technology.
Sigma-Aldrich has Announced an Exclusive Partnership with Atlas Antibodies
          Sigma-Aldrich has announced an exclusive partnership with Atlas Antibodies to distribute Prestige AntibodiesTM—developed by the Human Proteome Resource—to the proteomics and cell biology research communities. Initially consisting of 1800 antibodies, the library will grow by several thousand per year with the goal of producing at least one antibody to all 22,000 nonredundant human proteins by 2015.


Advertise: If you would like to sponsor or advertise in this newsletter, contact Sandy Galla.

To subscribe for FREE to one of our publications please click here.
To subscribe to one of our newsletters please click here.
Copyright © 2008 by International Scientific Communications, Inc., 30 Controls Drive, Shelton, Connecticut 06484, Phone: 203-926-9300. All rights reserved. Reproduction in whole or in part without written permission from International Scientific Communications, Inc. is prohibited.

To unsubscribe, CLICK HERE or if the e-mail address is not clickable, simply copy the text to the right of the 'mailto:' command and paste it into your e-mail application and hit send. You will be taken off the list immediately. Thank you!