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December 4, 2008

In This Issue...

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Digital Microscope Industry Application Guides
Click Here for More Information About Miele

Digital microscope technology has changed the way images are created, processed and displayed. Three 16-page guides from KEYENCE describe applications in 6 industries using a problem/solution approach. Incorporating advancements, unavailable with conventional microscopes, the new KEYENCE VHX-600 Digital Microscope is an all-in-one design. It provides benefits such as a high depth-of-field, 3D image composition, surface analysis with calibrated topographic displays, particle counting and on-screen measurements. New algorithms optimize illumination, image display and suppress glare.

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Contact Information
Keyence
Tel.: 888-539-3623
E-mail: keyence@keyence.com
www.keyence.com

What is "Hot" in Column Technologies for Liquid Chromatography?

by Frantisek Svec

It has been just over 100 years since Russian botanist Mikhail Semionovich Tswett invented the separation technique that he named chromatography. This term combines two Greek words, χηρομα (chroma) and γραπηειν a (graphein), meaning literally "color writing or recording." Tswett defined his approach the following way: "A method which separates different components on an adsorptive column in a flow system is a chromatographic method." Unfortunately, his approach did not attract much attention and remained unnoticed for a long time. Despite some experimental work during the 1930s, the major thrust came only after World War II. The seminal works of Archer J.P. Martin and Robert Synge that launched the era of modern gas and liquid chromatography were awarded the Nobel Prize in 1952. The following developments then led to rapid acceptance of this separation method. Today, chromatography is the third most widely used analytical technique, surpassed only by weighing and pH measurement…

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PerkinElmer Introduces Environmental Market Web Site

PerkinElmer Life and Analytical Sciences, a global leader in application focused measurement and analysis solutions, has introduced its enhanced environmental market Web site at www.perkinelmer.com/environmental. The site provides improved functionality and searching capabilities to enable environmental scientists to quickly obtain information on regulatory compliance, methods or standards, applications, and product information.

Drying Equipment Catalog
AdvertImage4

A catalog describes desiccants and related drying equipment for drying solids, liquids, and gases for protecting equipment and materials from the effects of moisture. Included are gas dryers, gas purifiers, balance desiccators, vent dryers for bulk storage, and desiccant bags.

Contact Information
W.A. Hammond Drierite Co., Ltd.
Tel.: 937-376-2927
Fax: 937-376-1977
www.drierite.com

An Immunoaffinity Capillary Electrophoresis Biomarker
Analyzer for Use in Toxicoproteomics Research

by Norberto A. Guzman

The slow pace of discovery of new protein biomarkers of toxicity or "toxicity signature protein/peptides" is partially due to the lack of high-throughput and high-sensitivity biomarker devices. Traditional proteomics platforms have been very useful, but there is a general consensus among scientists that significant improvements are needed to further our research into the understanding of injurious agents and how they affect biological systems during toxicity and disease. Some of the drawbacks of individual technologies have prompted investigators to use complementary multiple proteomics platforms that can bring more data to bear upon toxicological problems…

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The BINDER GmbH Innovation Reward

The BINDER GmbH Innovation Reward recognizes excellent achievement in cell biology relating to the use and application of cell cultures. Potential candidates are requested to submit their documentation with a CV and cover letter by January 15, 2009, by e-mail to dgz@dkfz.de or to Deutsche Gesellschaft für Zellbiologie e.V., Sekretariat, Frau Reichel-Klingmann, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.

Industrial Problem Solving of Polymeric Materials: Probing micro and nano-scale thermal properties
Complimentary Webinar
probe3
Date: Wednesday Oct 29, 2008
Time: 11:00 am EST
Duration: 1 hour
Presenters:
Dr. Louis T. Germinario, Sr. Scientist, Eastman Chemical
Dr. Craig Prater, CTO, Anasys Instruments

Developing polymeric materials for today’s competitive environment requires solving complex characterization problems. Learn how the breakthrough technique of localized thermal analysis is being used to help solve critical problems in polymer materials in applications ranging from Flat Panel Displays; Automotive Coatings; Polymer Haze/Gels in Medical Packaging; Thermosets and Weathering. This informative webinar will discuss both the award winning technique and how it is being used by scientists in industrial labs as a complement to other techniques.

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Making Single-Molecule Sequencing a Reality
by Avak Kahvejian and Steve Kellett

The quest to directly sequence individual strands of DNA has challenged genomic technologists for decades. All traditional and "next-generation" sequencing technologies require DNA samples to be amplified numerous times to make many copies of the original molecules, which, only then, can be detected and sequenced. Eliminating these copying steps for genetic analysis would not only reduce the costs and complexity of sample preparation, but would also avoid the errors and biases inherent in the amplification and image analysis process, producing data more closely reflective of the actual biology under study…

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Guava Technologies, Inc. Reaches Agreement With
Hudson Control Group

Guava Technologies, Inc. has reached an agreement with Hudson Control Group to provide drug discovery researchers with an automated solution for cellular analyses. The new cell analysis system delivers both sample preparation and cell analysis technologies directly to the laboratory benchtop, and is compatible with a range of Guava® turnkey assays in 96-well format.

BioTek Instruments Introduces EL406™ Microplate Washer Dispenser
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Efficiency and productivity are increased with BioTek Instrument’s new EL406™ Microplate Washer Dispenser.  This automation friendly, multifunctional instrument uniquely combines the industry standard ELx405™ Select CW Washer with a peristaltic reagent pumping system and two highly accurate syringe drive dispensers.  The wash module includes BioTek’s patented Dual-Action™ design for a variety of plate formats along with optimized flow rates for cell based applications as well as up to 4 wash buffers for complex wash routines.

For more information visit www.biotek.com/mynewbiotek.

Contact Information
BioTek
Tel.: 888-451-5171
www.biotek.com

High-Throughput Cell Cycle Analysis Using a Microplate Cytometer
by Paul Wylie

The traditional method of determining the cell cycle phase of individual cells is by quantifying their total DNA content using flow cytometry. For screening purposes, however, flow cytometry has several shortcomings, most notably, low throughput, the requirement for a large number of cells, and the inability to analyze adherent cell lines in situ…

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Detecting the Future of Bioscience
by Gabriella Armin

The potential to use antibodies as research tools has been known since the early 1890s, when Karl Landsteiner used antibodies to distinguish between the ortho and meta configurations of groups on benzene rings. Concurrently, Emil von Behring and Shibasaburo Kitasato demonstrated antibody-mediated immunity against diphtheria and tetanus toxins, culminating in Paul Ehrlich's proposal that antibodies could be used as "magic bullets" to target and defeat human diseases…

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